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1985年至1987年期间,大亚特兰大地区10岁儿童脑瘫的患病率。

Prevalence of cerebral palsy among ten-year-old children in metropolitan Atlanta, 1985 through 1987.

作者信息

Murphy C C, Yeargin-Allsopp M, Decouflé P, Drews C D

机构信息

Office of Epidemiology, Georgia Department of Human Resources, Atlanta.

出版信息

J Pediatr. 1993 Nov;123(5):S13-20. doi: 10.1016/s0022-3476(05)80892-3.

Abstract

The Metropolitan Atlanta Developmental Disabilities Study was a population-based study (1985 through 1987) to determine the prevalence of five developmental disabilities among 10-year-old children. The disabilities included cerebral palsy, mental retardation, visual impairment, hearing impairment, and epilepsy. The prevalence of cerebral palsy (CP) and a description of the children with CP are reported here. Using a record review approach, we identified 204 10-year-old children with CP (resulting in a prevalence of 2.3 per 1000). The rate of CP was significantly higher among boys (prevalence odds ratio = 1.5; 95% confidence interval = 1.1, 2.0), and the rate was also higher among black children than white children (prevalence odds ratio = 1.3; 95% confidence interval = 1.0, 1.7). Thirty-three of the children (16%) acquired CP postnatally; these children were more likely to be black or male. The gender and racial differences found for acquired CP were greater than those for congenital CP. Approximately 75% of the children had one of the other four disabilities studied; 65% of the children were mentally retarded, 46% had epilepsy, and 15% had a sensory impairment. Our multiple-source method of identifying children with CP gave us a population-based sample from which to determine the prevalence of the condition and to study factors that are associated with CP.

摘要

大亚特兰大发育障碍研究是一项基于人群的研究(1985年至1987年),旨在确定10岁儿童中五种发育障碍的患病率。这些障碍包括脑瘫、智力迟钝、视力障碍、听力障碍和癫痫。本文报告了脑瘫(CP)的患病率以及CP患儿的描述。通过记录回顾方法,我们确定了204名10岁的CP患儿(患病率为每1000人中有2.3人)。男孩中的CP发病率显著更高(患病率比值比=1.5;95%置信区间=1.1,2.0),黑人儿童中的发病率也高于白人儿童(患病率比值比=1.3;95%置信区间=1.0,1.7)。33名儿童(16%)在出生后患上CP;这些儿童更可能是黑人或男性。后天性CP中发现的性别和种族差异大于先天性CP。约75%的儿童患有研究中的其他四种障碍之一;65%的儿童智力迟钝,46%患有癫痫,15%有感觉障碍。我们识别CP患儿的多源方法为我们提供了一个基于人群的样本,从中可以确定该疾病的患病率,并研究与CP相关的因素。

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