Bader C, Monet J D, Chanard J, Funck-Brentano J L
C R Acad Hebd Seances Acad Sci D. 1976 Jun 21;282(23):2099-102.
A cytosolic colchicine-binding protein has been studied in Porcine parathyroid glands. The molecular weight of this protein is 110,000 dalton with a 6 S sedimentation constant. Its colchicine affinity is 1.3 X 10(6) l/mole at 37 degrees C. Polymerization-depolymerization kinetics and vinblastin sulfate-induced precipitation are the same as that of a tubulin.
对猪甲状旁腺中的一种胞质秋水仙碱结合蛋白进行了研究。该蛋白的分子量为110,000道尔顿,沉降常数为6S。在37℃时,其对秋水仙碱的亲和力为1.3×10⁶升/摩尔。聚合-解聚动力学和硫酸长春碱诱导的沉淀与微管蛋白相同。