Pergami A, Gala C, Burgess A, Durbano F, Zanello D, Riccio M, Invernizzi G, Catalan J
Department of Psychological Medicine, Chelsea and Westminster Hospital, Charing Cross & Westminster Medical School (University of London), U.K.
J Psychosom Res. 1993 Oct;37(7):687-96. doi: 10.1016/0022-3999(93)90097-y.
The aim of the investigation was to study the prevalence of current and past psychiatric morbidity and psychosocial problems in HIV seropositive (HIV +ve) asymptomatic women. A cross-sectional controlled study including 57 HIV +ve women belonging to CDC group II and III (43 intravenous drug users and 14 non-IVDUs heterosexuals) and 23 HIV -ve women (15 intravenous drug users and 8 non-IVDUs heterosexuals) is reported. Outcome measures included, past psychiatric history, current psychological status (Zung Anxiety and Depression scales, Symptom Check List 90-Revised), Social Supports and Locus of Control Scales, and information on changes in work, social and sexual life after HIV testing. Results showed that HIV +ve women differed very little from HIV -ve controls regarding outcome measures and indeed for some variables HIV infected women had lower levels of psychological morbidity. Multiple regression analyses showed that alcohol misuse and a predominantly external locus of control accounted for the 29% of the variance of psychiatric distress (F = 9.23, p < 0.0006). The implications of the findings are discussed.
该调查的目的是研究HIV血清反应阳性（HIV+）无症状女性当前和既往精神疾病发病率及心理社会问题。报告了一项横断面对照研究，该研究纳入了57名属于疾病控制中心（CDC）II组和III组的HIV+女性（43名静脉吸毒者和14名非静脉吸毒的异性恋者）以及23名HIV阴性女性（15名静脉吸毒者和8名非静脉吸毒的异性恋者）。结果指标包括既往精神病史、当前心理状态（zung焦虑和抑郁量表、症状自评量表90修订版）、社会支持和控制点量表，以及HIV检测后工作、社交和性生活变化的信息。结果显示，在结果指标方面，HIV+女性与HIV阴性对照差异很小，实际上对于某些变量，HIV感染女性的心理疾病水平较低。多元回归分析表明，酒精滥用和主要为外部控制点占精神痛苦方差的29%（F=9.23，p<0.0006）。讨论了研究结果的意义。
