Reif J S, Tsongas T A, Anger W K, Mitchell J, Metzger L, Keefe T J, Tessari J D, Amler R
Department of Environmental Health, Colorado State University, Fort Collins 80523.
J Toxicol Environ Health. 1993 Oct-Nov;40(2-3):413-22. doi: 10.1080/15287399309531808.
Communities surrounding the Rocky Mountain Arsenal (RMA), a Superfund site in Colorado, were studied in order to determine whether exposures to mercury were greater among persons who resided there than among residents of a comparison area 12-15 miles distant. From a census-based stratified random sample, 469 persons were interviewed and urine samples were obtained for biomonitoring. Mercury was detected in urine from 32 (6.8%) of the 469 persons sample at a detection limit of 5 ppb. Trace levels of mercury (detectable, but nonquantifiable) were found in 80 (17.1%) of the persons sampled. Neither the frequency of detection, the arithmetic mean, nor the geometric mean value for urine mercury was found to be statistically different when persons living near the site were compared to persons from the more distant comparison area. The risk of mercury exposure associated with demographic variables, residence, occupation, hobbies, dietary habits, water supply, housing, and activity patterns was evaluated. In the second stage of the evaluation, the Neurobehavioral Core Test Battery (NCTB) is being used to assess individual functional deficits and nervous system disorders associated with exposure to mercury and other neurotoxic chemicals.
落基山兵工厂（RMA）是科罗拉多州的一个超级基金污染场地，为了确定居住在该地的人群接触汞的程度是否高于距离此地12 - 15英里的对照区域居民，对其周边社区进行了研究。从基于人口普查的分层随机样本中，选取了469人进行访谈，并采集尿液样本用于生物监测。在469人的样本中，有32人（6.8%）的尿液中检测到汞，检测限为5 ppb。在80人（17.1%）的样本中发现了痕量汞（可检测到，但无法定量）。将场地附近居民与距离更远的对照区域居民相比，尿液汞的检测频率、算术平均值和几何平均值在统计学上均无差异。评估了与人口统计学变量、居住情况、职业、爱好、饮食习惯、供水、住房和活动模式相关的汞接触风险。在评估的第二阶段，正使用神经行为核心测试组（NCTB）来评估与接触汞及其他神经毒性化学物质相关的个体功能缺陷和神经系统疾病。
