用电模型模拟神经纤维的传导速度特性。

Simulation of the conduction velocity properties of nerve fibres by an electrical model.

作者信息

Pollak V A, Ferbert A, Schulze-Clewing J

机构信息

Department of Biomedical Engineering, University of Saskatchewan, Saskatoon, Canada.

出版信息

Med Biol Eng Comput. 1993 Jul;31(4):388-91. doi: 10.1007/BF02446693.

DOI:10.1007/BF02446693

PMID:8231302

Abstract

The paper presents a simple electrical circuit model from which the relationship between the diameter of the axon and its conduction velocity can be derived. The model is primarily intended for the larger myelinated fibres in peripheral nerves. However, a simplified model is also shown for nonmyelinated fibres, where the relationship is quite different. In the conclusion some qualitative considerations are presented for thin myelinated fibres with a slow velocity of conduction. The conduction velocity/diameter relationship of these fibres gradually approaches that for nonmyelinated fibres with decreasing diameter.

摘要

本文提出了一个简单的电路模型，从中可以推导出轴突直径与其传导速度之间的关系。该模型主要适用于外周神经中较大的有髓纤维。然而，文中也给出了无髓纤维的简化模型，其关系有很大不同。在结论部分，针对传导速度较慢的细有髓纤维给出了一些定性的考量。随着直径减小，这些纤维的传导速度/直径关系逐渐趋近于无髓纤维的关系。