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[继发性甲状旁腺功能亢进的新手术策略]

[New surgical strategy for secondary hyperparathyroidism].

作者信息

Yamamoto O, Oguchi K, Korematsu M, Hashimoto M, Hosoda Y, Mimura T, Ito K

机构信息

Department of Surgery, Social Insurance Saitama Chuo Hospital, Renal Center of SISCH, Urawa, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1993 Oct;94(10):1118-24.

PMID:8232186
Abstract

Extopic parathyroid glands and rudimentary glands which are not detected during initial parathyroidectomy may develop hyperplasia in the future, causing recurrence of hyperthyroidism. We have devised an improved surgical strategy to prevent the recurrence of hyperparathyroidism. The strategy is to dissect all central lymph nodes and fatty tissue according to the procedure of the dissection of thyroid cancer. The upper level of the dissection area is the upper edge of the thyroid cartilage and the lateral level of the dissection includes the lateral edge of the bilateral carotid sheath. Bilateral transcervical thymectomy is always included in this strategy. Upon confirming that more than 4 glands have been removed by intraoperative stamp cytology, total parathyroidectomy is terminated and 80 mg of glands is autotransplanted to the muscle of one forearm. We have performed this operation on 30 patients since 1987. More than 4 glands could be extirpated in every case, and supernumerary glands were detected in 6 cases (7 glands in 1 case and 5 glands in 4 cases). We have had no operative side effects in this series of 30 patients, and we have not experienced any persistent or recurrent hyperparathyroidism after any of these operations.

摘要

初次甲状旁腺切除术中未发现的异位甲状旁腺和发育不全的甲状旁腺日后可能会发生增生,导致甲状旁腺功能亢进复发。我们设计了一种改进的手术策略来预防甲状旁腺功能亢进复发。该策略是按照甲状腺癌的手术步骤切除所有中央淋巴结和脂肪组织。手术区域的上界为甲状软骨上缘,外侧界包括双侧颈动脉鞘外侧缘。双侧经颈胸腺切除术始终包含在该策略中。术中通过印片细胞学检查确认已切除4个以上甲状旁腺后,终止甲状旁腺全切术,并将80mg甲状旁腺组织自体移植至一侧前臂肌肉。自1987年以来,我们已对30例患者实施了该手术。每例均能切除4个以上甲状旁腺,6例发现有额外甲状旁腺(1例7个,4例5个)。在这30例患者中,我们未出现任何手术相关副作用,且术后均未出现持续性或复发性甲状旁腺功能亢进。

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