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[通过将内细胞团注射到囊胚中获得的嵌合小鼠的分析]

[An analysis of chimeric mice obtained by the injection of the inner cell mass into the blastocyst].

作者信息

Mitalipov Sh M, Fedorov L M, Strel'chenko N S

出版信息

Ontogenez. 1993 Sep-Oct;24(5):5-10.

PMID:8233307
Abstract

Mouse chimeras were produced using injections of ICM cells into blastocysts. Chimerism of resulting animals was determined by their coat color and spectrum of glucosephosphate isomerase isoenzymes. The use of modifications of the injection method for solving different genetic and embryological problems is discussed.

摘要

通过将内细胞团(ICM)细胞注射到囊胚中来制备小鼠嵌合体。通过其毛色和葡萄糖磷酸异构酶同工酶谱来确定所得动物的嵌合情况。本文讨论了使用注射方法的改进来解决不同的遗传和胚胎学问题。

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