Assaf A A, Tabbara K F, el-Hazmi M A
Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ophthalmic Paediatr Genet. 1993 Jun;14(2):81-6. doi: 10.3109/13816819309042907.
Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency plays an important biochemical role in the metabolism of the lens. Controversies exist in the literature on the possible association between G-6-PD deficiency and the development of cataracts. The authors present ten patients, aged between infancy and 40 years of age, who were admitted for bilateral congenital or presenile cataracts. These patients had no ocular or systemic disease which might have caused their cataract. The only systemic finding they had was G-6-PD deficiency. Two other patients among the families described suffered from bilateral congenital or presenile cataracts with no G-6-PD deficiency. This deficiency state does not appear to play a role in the production of their cataracts.
葡萄糖-6-磷酸脱氢酶（G-6-PD）缺乏症在晶状体代谢中起着重要的生化作用。关于G-6-PD缺乏症与白内障发生之间可能存在的关联，文献中存在争议。作者介绍了10例年龄在婴儿期至40岁之间因双侧先天性或早老性白内障入院的患者。这些患者没有可能导致其白内障的眼部或全身性疾病。他们唯一的全身性发现是G-6-PD缺乏症。在所描述的这些家庭中，另外两名患者患有双侧先天性或早老性白内障，但没有G-6-PD缺乏症。这种缺乏状态似乎在他们白内障的形成过程中不起作用。
