Dawson D C, Curran P F
J Membr Biol. 1976 Aug 26;28(2-3):295-307. doi: 10.1007/BF01869702.
Na transport by the isolated toad colon has been studied by measuring transmural Na fluxes and by direct measurement of the Na influx across the mucosal border. Net Na transport accounts for 88% of the short circuit current in the presence and in the absence of exogenous aldosterone. Na influx across the mucosal border appears to consist of two components. One component is highly correlated with short circuit current, is a saturable function of mucosal Na concentration, and is inhibited by lithium ions in the mucosal medium. The second component is a linear function of mucosal Na concentration, is unaffected by lithium, and is apparently not related to net Na transport by the tissue.
通过测量跨壁钠通量以及直接测量跨黏膜边界的钠内流，对离体蟾蜍结肠的钠转运进行了研究。无论有无外源性醛固酮，钠的净转运均占短路电流的88%。跨黏膜边界的钠内流似乎由两个部分组成。一个部分与短路电流高度相关，是黏膜钠浓度的饱和函数，并受到黏膜介质中锂离子的抑制。第二个部分是黏膜钠浓度的线性函数，不受锂的影响，且显然与组织的钠净转运无关。
