Wendel R T, Patel A C, Kelly N E, Salzano T C, Wells J W, Novack G D
Mercy Eye Foundation, Sacramento, CA.
Ophthalmology. 1993 Nov;100(11):1671-6. doi: 10.1016/s0161-6420(93)31419-3.
To surgically treat patients with macular holes, the authors previously reported both anatomic (re-attachment) and visual success (2 lines of improvement) in a series of 52 eyes. They now have operated on an additional 118 eyes using similar techniques, for a total of 170 eyes.
After ophthalmologic examination and history, the authors operated on suitable patients. The surgical objectives included relief of all tangential traction and retinal tamponade with intraocular gas. All eyes were followed for at least 6 months postoperatively.
In the total population of 170 eyes, anatomic success was achieved in 73% and vision improved at least two lines in 55%. Twenty-nine percent (49/170) of patients had a visual acuity of 20/40 or better at last examination. Patients with symptoms of less than 6 months' duration managed better than those with symptoms of longer duration (P = 0.3001). In the former group of 66 eyes, anatomic success was achieved in 80% (n = 53), whereas visual acuity improved at least two lines in 68% (n = 45) and at least four lines in 55% (n = 36).
The authors suggest that macular hole surgery may provide meaningful improvement in visual acuity in most patients, especially in those whose symptoms are of less than 6 months' duration.
为了通过手术治疗黄斑裂孔患者,作者此前报道了一系列52只眼中的解剖学成功(视网膜复位)和视觉效果成功(视力提高2行)。他们现在使用类似技术又对118只眼进行了手术,总共170只眼。
在进行眼科检查和了解病史后,作者对合适的患者进行手术。手术目标包括解除所有切线方向的牵拉,并使用眼内气体进行视网膜填塞。所有眼睛术后至少随访6个月。
在总共170只眼中,73%实现了解剖学成功,55%的视力至少提高了2行。29%(49/170)的患者在最后一次检查时视力达到20/40或更好。症状持续时间不到6个月的患者比症状持续时间较长的患者治疗效果更好(P = 0.3001)。在66只眼的前一组中,80%(n = 53)实现了解剖学成功,而68%(n = 45)的视力至少提高了2行,55%(n = 36)的视力至少提高了4行。
作者认为黄斑裂孔手术可能会使大多数患者的视力得到有意义的改善,尤其是那些症状持续时间不到6个月的患者。