Dormehl I C, van Gelder A L, Hugo N, Weller R, Stanton J J, Beverley G H, Clausen M
AEC Institute for Life Sciences, University of Pretoria, South Africa.
Nuklearmedizin. 1993 Oct;32(5):222-6.
This study assesses the diagnostic potential of a tomographic technique with phase analysis to detect premature electroventricular contraction patterns simulated by pacing in the baboon. The data of gated SPECT were analysed by backprojection of the Fourier coefficients, followed by angulation and integration to thick slices of the entire ventricular mass yielding separate ventricular contraction patterns in three perpendicular views. Electrodes were implanted in each baboon: at the sinoatrial node; posterior, left ventricular; anterior left ventricular; on the left and the right lateral ventricular walls. The atrium was stimulated throughout at a fixed rate. Subsequent ventricular stimuli followed during the QRS complex, such to invoke the appearance of pre-excitation QRS morphology. The first points of activation (FPA) from this algorithm were correctly detected for the RV, for the anterior and posterior sites, although the latter two manifested first points in the RV. LV pacing manifested also as a FPA in the RV, but was followed by a true subsequent point in the LV.
本研究评估了一种具有相位分析的断层扫描技术在检测狒狒中通过起搏模拟的室性早搏模式方面的诊断潜力。门控单光子发射计算机断层扫描（SPECT）数据通过傅里叶系数的反投影进行分析，然后进行角度调整和积分，得到整个心室质量的厚切片，在三个垂直视图中产生单独的心室收缩模式。在每只狒狒身上植入电极：位于窦房结；左心室后壁；左心室前壁；左右心室壁上。整个心房以固定频率进行刺激。随后在QRS复合波期间进行心室刺激，以引发预激QRS形态的出现。尽管后两个部位的首次激活点在右心室（RV），但该算法对右心室、前壁和后壁部位的首次激活点（FPA）进行了正确检测。左心室（LV）起搏在右心室也表现为一个首次激活点，但随后在左心室出现了一个真正的后续点。
