在四环素的过氧化代谢过程中，发光伴随着氧气的摄取。
Light emission accompanies oxygen uptake during the peroxidative metabolism of tetracyclines.
作者信息
Gilio V E, Cilento G
机构信息
Department of Biochemistry, Instituto de Química, Universidade de São Paulo, Brazil.
出版信息
Photochem Photobiol. 1993 Sep;58(3):446-9. doi: 10.1111/j.1751-1097.1993.tb09588.x.
Tetracycline molecules offer several sites for peroxidative metabolism of the type known to lead to oxygen consumption and electronic excitation. Accordingly, when tetracycline and chlortetracycline were exposed to horseradish peroxidase in the presence of hydrogen peroxide, oxygen was taken up and light emission was observed. The overall quantum yield of chemiluminescence is on the order of 10(-6), but that of chemiexcitation may be orders of magnitude higher as suggested by studies of sensitized emission. Given the widespread distribution of peroxidases, the formation of highly reactive metabolites of tetracycline may have biological importance.
四环素分子具有几个位点，可进行那种已知会导致耗氧和电子激发的过氧化代谢。因此，当四环素和金霉素在过氧化氢存在的情况下暴露于辣根过氧化物酶时，会消耗氧气并观察到发光现象。化学发光的总量子产率约为10^(-6)，但如敏化发射研究所表明的，化学激发的量子产率可能要高几个数量级。鉴于过氧化物酶分布广泛，四环素高反应性代谢产物的形成可能具有生物学意义。
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