Set P A, Flower C D, Smith I E, Chan A P, Twentyman O P, Shneerson J M
Department of Radiology, Addenbrooke's Hospital, Cambridge, England.
Radiology. 1993 Dec;189(3):677-80. doi: 10.1148/radiology.189.3.8234690.
A prospective study was performed to compare results of computed tomography (CT) and fiberoptic bronchoscopy in diagnosis of cancer in patients with hemoptysis.
Ninety-one patients (64 men, 27 women) with hemoptysis underwent thin-section CT and fiberoptic bronchoscopy.
CT scans demonstrated all 27 tumors seen at bronchoscopy and an additional seven, five of which were beyond bronchoscopic range. In patients with normal chest radiographs, bronchial carcinoma was detected in 5% at both bronchoscopy and CT. In patients with abnormal findings on radiographs, bronchoscopy allowed both location and histologic diagnosis in 78% of carcinomas but was unreliable in locating peripheral tumors demonstrated at CT. CT was insensitive in demonstrating early mucosal abnormalities, bronchitis, squamous metaplasia, and a benign papilloma, all detected at bronchoscopy.
The initial examination should be bronchoscopy when there is high clinical suspicion of carcinoma and relevant radiographic abnormality, and CT when strong clinical suspicion of carcinoma is not substantiated at bronchoscopy in patients with normal findings on chest radiographs.
进行一项前瞻性研究,比较计算机断层扫描(CT)和纤维支气管镜检查在咯血患者癌症诊断中的结果。
91例咯血患者(64例男性,27例女性)接受了薄层CT和纤维支气管镜检查。
CT扫描显示了支气管镜检查发现的所有27个肿瘤,另外还有7个,其中5个超出了支气管镜检查范围。在胸部X线片正常的患者中,支气管镜检查和CT检查均发现5%的患者患有支气管癌。在X线片有异常发现的患者中,支气管镜检查在78%的癌患者中实现了定位和组织学诊断,但在定位CT显示的周围性肿瘤方面不可靠。CT在显示早期黏膜异常、支气管炎、鳞状化生和良性乳头状瘤方面不敏感,这些均在支气管镜检查中被发现。
当临床高度怀疑癌症且有相关影像学异常时,初始检查应选择支气管镜检查;当胸部X线片正常的患者支气管镜检查未证实有强烈临床怀疑的癌症时,则应选择CT检查。