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系统性红斑狼疮中的肺泡出血

Pulmonary alveolar hemorrhage in systemic lupus erythematosus.

作者信息

Schwab E P, Schumacher H R, Freundlich B, Callegari P E

机构信息

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia.

出版信息

Semin Arthritis Rheum. 1993 Aug;23(1):8-15. doi: 10.1016/s0049-0172(05)80022-8.

Abstract

Pulmonary alveolar hemorrhage (PAH) is a rare and often fatal presenting feature of systemic lupus erythematosus (SLE). Reported mortality rates are extremely high, 70% to 90%. Death frequently occurs within the first several days of the hemorrhage. The hospital records of all inpatients with PAH and SLE between April 1986 and May 1991 at the Hospital of the University of Pennsylvania were reviewed. The complete resolution of PAH and the 75% survival rate found in this study is in marked contrast to previous reports. This experience suggests that patients with PAH and SLE may have a better prognosis than previously reported.

摘要

肺泡出血(PAH)是系统性红斑狼疮(SLE)一种罕见且往往致命的表现特征。报告的死亡率极高,为70%至90%。死亡常常发生在出血后的头几天内。对1986年4月至1991年5月期间宾夕法尼亚大学医院所有PAH合并SLE住院患者的医院记录进行了回顾。本研究中PAH的完全缓解以及75%的生存率与之前的报告形成了显著对比。这一经验表明,PAH合并SLE患者的预后可能比之前报告的要好。

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