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Sequence similarity of phospholipase A2 activating protein and the G protein beta-subunits: a new concept of effector protein activation in signal transduction?

作者信息

Peitsch M C, Borner C, Tschopp J

机构信息

Institute of Biochemistry, University of Lausanne, Epalinges, Switzerland.

出版信息

Trends Biochem Sci. 1993 Aug;18(8):292-3. doi: 10.1016/0968-0004(93)90038-o.

DOI:10.1016/0968-0004(93)90038-o
PMID:8236442
Abstract
摘要

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Sequence similarity of phospholipase A2 activating protein and the G protein beta-subunits: a new concept of effector protein activation in signal transduction?磷脂酶A2激活蛋白与G蛋白β亚基的序列相似性：信号转导中效应蛋白激活的新概念？
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The cytotoxic enterotoxin of Aeromonas hydrophila induces proinflammatory cytokine production and activates arachidonic acid metabolism in macrophages.嗜水气单胞菌的细胞毒性肠毒素可诱导巨噬细胞产生促炎细胞因子并激活花生四烯酸代谢。
Infect Immun. 2000 May;68(5):2808-18. doi: 10.1128/IAI.68.5.2808-2818.2000.
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Cholera toxin induces synthesis of phospholipase A2-activating protein.
霍乱毒素诱导磷脂酶A2激活蛋白的合成。
Infect Immun. 1996 Jun;64(6):2137-43. doi: 10.1128/iai.64.6.2137-2143.1996.
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Molecular genetic analysis of volatile-anesthetic action.挥发性麻醉药作用的分子遗传学分析
Mol Cell Biol. 1996 Jul;16(7):3446-53. doi: 10.1128/MCB.16.7.3446.
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Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.异源三聚体G蛋白的βγ亚基与布鲁顿酪氨酸激酶的PH结构域的结合。
Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11256-60. doi: 10.1073/pnas.91.23.11256.
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