Rao R V, Anupindi L, Chatterjee A, Varghese G K, Krishnanand B R
Kasturba Medical College, South Karnataka, India.
Trop Geogr Med. 1993;45(4):180-1.
A 26-year-old male presented with oedema, massive albuminuria and microscopic haematuria. Kidney biopsy revealed enlarged cellular glomeruli infiltrated by polymorphs and eosinophils with focal fibrin deposits along the basement membrane. Microfilariae were seen in the lumen of few glomerular capillaries. Antistreptolysin titre was negative. The absence of other aetiological factors and presence of microfilariae within glomeruli suggests that nephrotic syndrome may be due to a filarial nephritis.
一名26岁男性出现水肿、大量蛋白尿和镜下血尿。肾活检显示肾小球细胞增大，有中性粒细胞和嗜酸性粒细胞浸润，沿基底膜有局灶性纤维蛋白沉积。在少数肾小球毛细血管腔内可见微丝蚴。抗链球菌溶血素滴度为阴性。由于不存在其他病因因素且肾小球内有微丝蚴，提示肾病综合征可能是由丝虫性肾炎所致。
