与罗阿丝虫病相关的继发性塌陷性肾小球病。

Secondary collapsing glomerulopathy associated with Loa loa filariasis.

作者信息

Pakasa N M, Nseka N M, Nyimi L M

机构信息

Department of Pathology, University Hospital of Kinshasha, Democratic Republic of Congo, Zaire.

出版信息

Am J Kidney Dis. 1997 Dec;30(6):836-9. doi: 10.1016/s0272-6386(97)90090-1.

DOI:10.1016/s0272-6386(97)90090-1

PMID:9398129

Abstract

This is the first case of nonprimary collapsing focal segmental glomerulosclerosis (FSGS) associated with Loa loa filariasis. Loa loa micofilariae were detected on a blood smear after a patient presented with nephrotic syndrome (NS), microhematuria, and renal failure. The renal biopsy showed a collapsing glomerulopathy variant of FSGS. Microfilariae also were identified in renal microvasculature, including the afferent arterioles and the glomerular and peritubular capillaries.

摘要

这是首例与罗阿丝虫病相关的非原发性塌陷型局灶节段性肾小球硬化（FSGS）病例。一名出现肾病综合征（NS）、镜下血尿和肾衰竭的患者，其血涂片检测出罗阿丝虫微丝蚴。肾活检显示为FSGS的塌陷型肾小球病变体。在肾微血管（包括入球小动脉、肾小球和肾小管周围毛细血管）中也发现了微丝蚴。