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[葡萄球菌肽聚糖对电离辐射效应早期阶段肌浆网Ca2+-ATP酶活性的影响]

[Effect of staphylococcal peptidoglycan on the activity of Ca2+-ATP-ase from the sarcoplasmic reticulum in the early stages of ionizing radiation effect].

作者信息

Voĭtsits'kyĭ V M, Pozur V K, Kucherenko M Ie

出版信息

Ukr Biokhim Zh (1978). 1993 Mar-Apr;65(2):63-8.

PMID:8236533
Abstract

It is established that peptidoglycan of Staphylococcus aureus possess superficial activity and can render influence on the functional activity of biomembranes. It tends to increase Ca(2+)-ATP-ase activity in the sarcoplasmic reticulum membranes, but no changes have been observed in case of the enzyme solubilization. The effect of peptidoglycan was more expressed, if it was used in the early period of acute radiation injury (1 and 24 h) in a dose of 0.21 Cl/kg for samples with irradiation-induced decrease of Ca(2+)-ATP-ase activity.

摘要

已经确定,金黄色葡萄球菌的肽聚糖具有表面活性,并能对生物膜的功能活性产生影响。它倾向于增加肌浆网膜中Ca(2+)-ATP酶的活性,但在酶溶解的情况下未观察到变化。如果在急性辐射损伤的早期(1和24小时)以0.21 Cl/kg的剂量使用肽聚糖,对于Ca(2+)-ATP酶活性因辐射诱导而降低的样品,其效果更为明显。

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