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枸橼酸噻嘧啶对英国绵羊苯并咪唑耐药性线虫菌株的活性。

Activity of morantel citrate against strains of benzimidazole-resistant nematodes of sheep in the United Kingdom.

作者信息

Coles G C, Harris T J, Hong C

机构信息

Department of Parasitology, Central Veterinary Laboratory, Addelestone, Surrey.

出版信息

Vet Rec. 1993 Aug 14;133(7):156-7. doi: 10.1136/vr.133.7.156.

Abstract

The activity of morantel citrate (5.94 mg/kg base) was determined in laboratory tests against field isolates of benzimidazole-resistant nematodes. Its efficacies against adult and seven-day-old worms were 100 per cent and 100 per cent for Cooperia curticei, 95.1 per cent and 69.8 per cent for Haemonchus contortus and 100 per cent and 82 per cent for Ostertagia circumcincta. Morantel citrate was 100 per cent effective against benzimidazole-susceptible Nematodirus battus and Trichostrongylus vitrinus, and it reduced faecal egg counts by 97.9 per cent in sheep infected naturally with benzimidazole-resistant H contortus and O circumcincta.

摘要

在实验室测试中测定了枸橼酸噻嘧啶(5.94毫克/千克碱)对苯并咪唑抗性线虫田间分离株的活性。其对库珀短尾线虫成虫和7日龄虫体的疗效分别为100%和100%,对捻转血矛线虫为95.1%和69.8%,对环形奥斯特线虫为100%和82%。枸橼酸噻嘧啶对苯并咪唑敏感的巴氏细颈线虫和玻璃毛圆线虫的疗效为100%,并且使自然感染了苯并咪唑抗性捻转血矛线虫和环形奥斯特线虫的绵羊粪便虫卵计数减少了97.9%。

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