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对经贯叶连翘实验性中毒的绵羊的研究。

Studies of sheep experimentally poisoned with Hypericum perforatum.

作者信息

Kako M D, al-Sultan I I, Saleem A N

机构信息

Department of Pathology, College of Veterinary Medicine, University of Mosul, Iraq.

出版信息

Vet Hum Toxicol. 1993 Aug;35(4):298-300.

PMID:8236746
Abstract

Sheep given different dosages and frequencies of Hypericum perforatum had decreased hemoglobin, red blood cell count, packed cell volumes, total protein, glucose, cholesterol, triglycerides, and serum alkaline phosphotase activities. Blood urea nitrogen, sodium, potassium, bilrubin (total and direct), and the activities of aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase and gamma glutamyltransferase increased. Hemato-biochemical assays were useful diagnostic aids to determine the severity of this plant's toxic effects.

摘要

给予不同剂量和频率贯叶连翘的绵羊出现血红蛋白、红细胞计数、红细胞压积、总蛋白、葡萄糖、胆固醇、甘油三酯及血清碱性磷酸酶活性降低。血尿素氮、钠、钾、胆红素(总胆红素和直接胆红素)以及天冬氨酸转氨酶、丙氨酸转氨酶、乳酸脱氢酶和γ-谷氨酰转移酶活性升高。血液生化检测是确定该植物毒性作用严重程度的有用诊断辅助手段。

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