Frantsuzov V N, Krylov N L, Kalinin V P, Pomelov A V
Voen Med Zh. 1993 Sep(9):44-5, 80.
The article summarized the experience of treatment of 253 cases of trophic ulcers of lower extremities (patients' age 18-82). Surgical method was the main one. Operative interventions were oriented at the main point of pathogenesis in order to close the ulcer defect. Considering the abnormalities of microcirculation as a common component of pathogenesis, the authors substantiate the prolonged arterial infusion via large arterial branches, which were catheterized in 76 patients. It is recommended to perform gnotobiological isolation, immobilized protease, pulsed flow, ultrasonic cavitation, laser irradiation.
本文总结了253例下肢营养性溃疡（患者年龄18 - 82岁）的治疗经验。手术方法是主要治疗手段。手术干预针对发病机制的关键点，以闭合溃疡缺损。考虑到微循环异常是发病机制的共同组成部分，作者证实了通过大的动脉分支进行长时间动脉灌注，76例患者进行了动脉插管。建议进行无菌隔离、固定化蛋白酶、脉冲流、超声空化、激光照射。
