Angulo J C, López J I, Toledo J D, Flores N
Servicio de Urología, Santo Hospital Civil de Bilbao.
Actas Urol Esp. 1993 Sep;17(8):529-32.
This paper reviews our experience with the vesical cancer which develops on the diverticulum, a situation occurring in 1.5% of all vesical tumours in our setting. The condition's clinical features (diagnostic and therapeutic), usually detected in advanced stages, are emphasized. From a morphological point of view, histology of over half these tumours differs from the pure transitional one. There were two cases of pure transitional carcinoma, one small cells cancer, one squamous cells cancer and one with adenocarcinoma differentiating foci. Several sets of data, which include histological variability as well as presence of congenital diverticulum and urethral tumours, have led us to suspect the existence of morpho-genetical factors in the development of these neoplasias. However, the widely accepted carcinogenetic theory continues to be the most likely.
本文回顾了我们在膀胱憩室癌方面的经验,这种情况在我们所研究的所有膀胱肿瘤中占1.5%。文中强调了该病症通常在晚期才被发现的临床特征(诊断和治疗方面)。从形态学角度来看,超过半数此类肿瘤的组织学特征与单纯的移行细胞癌不同。其中有两例单纯移行细胞癌、一例小细胞癌、一例鳞状细胞癌以及一例伴有腺癌分化灶的病例。包括组织学变异性以及先天性憩室和尿道肿瘤的存在等几组数据,使我们怀疑这些肿瘤形成过程中存在形态发生学因素。然而,被广泛接受的致癌理论仍然是最有可能的。