胎儿生物物理评分。VI. 与产前脐静脉胎儿pH值的相关性。
Fetal biophysical profile score. VI. Correlation with antepartum umbilical venous fetal pH.
作者信息
Manning F A, Snijders R, Harman C R, Nicolaides K, Menticoglou S, Morrison I
机构信息
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Manitoba, Winnipeg, Canada.
出版信息
Am J Obstet Gynecol. 1993 Oct;169(4):755-63. doi: 10.1016/0002-9378(93)90002-z.
OBJECTIVE
Our objective was to determine the relationship, if any, between the fetal biophysical profile score and antepartum umbilical venous pH.
STUDY DESIGN
This was a prospective observational study conducted concurrently in two centers and involving two discrete high-risk groups of fetuses. Fetal biophysical profile scores were compared with umbilical venous pH values measured in blood obtained by immediate cordocentesis. A total of 493 paired observations of biophysical profile score and pH were made; 104 observations were of fetuses with intrauterine growth retardation and 389 observations were of fetuses with alloimmune anemia.
RESULTS
In both data sets there was a highly significant linear correlation between biophysical profile score and umbilical venous pH. Poor biophysical profile score performance (a score of 0 of 10) was always associated with a pH < 7.20, whereas the pH was always > 7.20 when the biophysical profile score was 10 of 10. Sequenced sensitivity of short-term biophysical variables in the detection of acidemia was observed.
CONCLUSION
The fetal biophysical profile score accurately predicts antepartum umbilical venous pH.
目的
我们的目的是确定胎儿生物物理评分与产前脐静脉pH值之间是否存在关系（若存在关系）。
研究设计
这是一项在两个中心同时进行的前瞻性观察性研究，涉及两组不同的高危胎儿。将胎儿生物物理评分与通过即时脐静脉穿刺获取的血液中测得的脐静脉pH值进行比较。共进行了493对生物物理评分和pH值的观察；其中104例观察对象为宫内生长受限胎儿，389例观察对象为同种免疫性贫血胎儿。
结果
在两个数据集中，生物物理评分与脐静脉pH值之间均存在高度显著的线性相关性。生物物理评分表现不佳（10分制得0分）总是与pH值<7.20相关，而当生物物理评分为10分制的10分时，pH值总是>7.20。观察到短期生物物理变量在检测酸血症方面的序列敏感性。
结论
胎儿生物物理评分可准确预测产前脐静脉pH值。
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