May R L, Goodman A H, Meindl R S
Department of Anthropology, Kent State University, Ohio 44242.
Am J Phys Anthropol. 1993 Sep;92(1):37-51. doi: 10.1002/ajpa.1330920104.
The effects of changes in nutritional and health status upon bone and enamel development are examined in a sample of 63 rural Guatemalan children (24 females, 39 males). The number of ossified hand-wrist centers at 3 years and the number of linear enamel hypoplasias (LEH) in approximately 0-3 year zones of developing teeth were used to monitor the response of bone mineralization and enamel matrix formation to illness and nutritional supplementation. Numbers of ossified centers and LEH were compared across sex, supplementation, and morbidity groups. Enamel matrix secretion responded positively to increased supplementation. Children who received less than 34.25 kcal/day in supplement had more LEH than those who received more supplement. No differences in ossification status were found between supplementation groups. These data suggest that enamel formation may be more sensitive to changes in nutritional status than is bone mineralization. Disruptions of bone and enamel formation were both associated with frequent illness. Children who were ill more than 3.6% of the time had more LEH and fewer ossified hand-wrist centers than children who were less frequently ill. Conclusions regarding relative environmental sensitivity must take into account the specific aspects of dental and skeletal development examined.
在63名危地马拉农村儿童（24名女性，39名男性）的样本中，研究了营养和健康状况变化对骨骼和牙釉质发育的影响。利用3岁时手部腕骨中心的骨化数量以及发育中牙齿约0 - 3岁区域的线性釉质发育不全（LEH）数量，来监测骨矿化和釉质基质形成对疾病和营养补充的反应。对骨化中心数量和LEH数量在性别、补充情况和发病情况组之间进行了比较。釉质基质分泌对增加补充有积极反应。补充量低于34.25千卡/天的儿童比补充量更多的儿童有更多的LEH。补充组之间在骨化状态上未发现差异。这些数据表明，釉质形成可能比骨矿化对营养状况变化更敏感。骨骼和牙釉质形成的破坏都与频繁患病有关。患病时间超过3.6%的儿童比患病频率较低的儿童有更多的LEH且手部腕骨中心骨化数量更少。关于相对环境敏感性的结论必须考虑所研究的牙齿和骨骼发育的具体方面。
