Elliott W M, Youson J H
Department of Zoology, University of Toronto, West Hill, Ontario, Canada.
Anat Rec. 1993 Oct;237(2):259-70. doi: 10.1002/ar.1092370213.
The results of this study were found to support the hypothesis put forth by Boenig (Z. Mikrosk-Anat. Forsch., 17:125-184, 1929) that the caudal pancreas of adult lamprey develops from the epithelium of the extrahepatic common bile duct in that the bile duct cells were found to undergo a great proliferation during the early stages of metamorphosis, with a large number of the cells incorporating 3H-thymidine. If the bile duct degenerated as suggested by Barrington (The Biology of Lampreys. Academic Press, London, pp. 135-169, 1972), this uptake would not be expected. The cranial pancreas was determined to develop in a similar manner to the larval islets, with formation of the islets taking place within the intestinal/diverticular epithelium. The newly formed islets would migrate into the surrounding connective tissue. During the later stages of metamorphosis a small number of cells was found to incorporate the tritiated thymidine within mature islets.
本研究结果支持博尼希（《组织学与解剖学研究》，17:125 - 184，1929年）提出的假说，即成年七鳃鳗的尾胰脏由肝外胆总管上皮发育而来，因为在变态早期发现胆管细胞大量增殖，大量细胞掺入了3H - 胸腺嘧啶核苷。如果如巴林顿（《七鳃鳗生物学》。学术出版社，伦敦，第135 - 169页，1972年）所提出的那样胆管退化，那么这种摄取是不会出现的。已确定头胰脏的发育方式与幼体胰岛相似，胰岛在肠/憩室上皮内形成。新形成的胰岛会迁移到周围的结缔组织中。在变态后期，发现少量细胞在成熟胰岛内掺入了氚标记的胸腺嘧啶核苷。
