化学固定和杀死耳内蟑螂：一项体外比较研究。
Chemical immobilization and killing of intra-aural roaches: an in vitro comparative study.
作者信息
Leffler S, Cheney P, Tandberg D
机构信息
Department of Emergency Medicine, University of New Mexico, Albuquerque.
出版信息
Ann Emerg Med. 1993 Dec;22(12):1795-8. doi: 10.1016/s0196-0644(05)80402-0.
STUDY OBJECTIVE
The treatment of live insects in patients' ears is controversial. To determine which chemical agent is most effective for immobilizing and killing intra-aural cockroaches, we carried out the following investigation.
DESIGN
An in vitro blinded comparative study.
INTERVENTIONS
A model was developed in which live cockroaches were submerged in microscope immersion oil, 2% lidocaine, 4% lidocaine, or 2% viscous lidocaine in a glass beaker. Responses of cockroaches were recorded with a video-cassette recorder and evaluated later by a blinded observer. Measured variables were time to death and time-integrated activity before death. Analysis was by analysis of variance with Tukey's procedure.
RESULTS
Four groups of 40 cockroaches each were exposed to each of the four agents. Microscope oil killed the insects most quickly (mean, 27.2 seconds; 95% confidence interval, 23.8 to 30.6). The other agents required more than 40 seconds and were inferior to oil (F = 15.5, P < .0001). Total activity was also least in the microscope oil group (F = 25.7, P < .0001).
CONCLUSION
Microscope immersion oil is the most effective agent for immobilizing and killing intra-aural cockroaches.
研究目的
治疗患者耳内活昆虫的方法存在争议。为确定哪种化学药剂对固定和杀死耳内蟑螂最有效，我们进行了以下调查。
设计
一项体外盲法对照研究。
干预措施
建立了一个模型，将活蟑螂置于玻璃烧杯中，分别浸泡于显微镜浸油、2%利多卡因、4%利多卡因或2%粘性利多卡因中。用盒式录像机记录蟑螂的反应，随后由一名盲法观察者进行评估。测量的变量为死亡时间和死前的时间积分活动。采用方差分析和Tukey法进行分析。
结果
四组蟑螂，每组40只，分别暴露于四种药剂中的一种。显微镜油杀死昆虫最快（平均27.2秒；95%置信区间，23.8至30.6）。其他药剂所需时间超过40秒，且不如油有效（F = 15.5，P <.0001）。显微镜油组的总活动量也最少（F = 25.7，P <.0001）。
结论
显微镜浸油是固定和杀死耳内蟑螂最有效的药剂。
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