Grimm A F, Katele K V, Lin H L
Basic Res Cardiol. 1976 Jul-Aug;71(4):381-8. doi: 10.1007/BF01910776.
The orientation of the muscle fiber bundles within the mammalian left ventricle was examined in a variety of mammals. The hearts were arrested in situ in animals with an intact thorax by means of an isotonic K+ solution perfused via the aorta and coronaries. The hearts were then fixed by formalin perfusion through the same vessels and the hearts embedded in gelatin. Serial sections were prepared perpendicular to the Apex-Valve axis. On close examination, the muscle fibers show the change in orientation from endocardium to epicardium previously described by others. In addition, the clefts and voids of the inner one-third to inner one-half of the left ventricular wall add another dimension to the fiber direction: the fiber bundles appear to take a curving course from the middle of the wall to the endocardial surface. This pattern was visible in all studied hearts. Speculations are made on the significance of this anatomic arrangement.
在多种哺乳动物中研究了哺乳动物左心室内肌纤维束的方向。通过经由主动脉和冠状动脉灌注等渗钾溶液，使胸腔完整的动物心脏原位停跳。然后通过相同血管用福尔马林灌注固定心脏，并将心脏嵌入明胶中。制备垂直于心尖 - 瓣膜轴的连续切片。仔细观察发现，肌纤维呈现出如前人所描述的从心内膜到心外膜方向的变化。此外，左心室壁内三分之一至内二分之一处的裂隙和空隙为纤维方向增添了另一个维度：纤维束似乎从壁的中部向心内膜表面呈弯曲走向。这种模式在所有研究的心脏中都可见。文中对这种解剖学排列的意义进行了推测。
