Shpitzer T, Stern Y, Cohen O, Levy R, Segal K, Feinmesser R
Department of Otolaryngology-Head and Neck Surgery, Beilinson Medical Center, Petah-Tiqva, Israel.
Ann Otol Rhinol Laryngol. 1993 Nov;102(11):870-2. doi: 10.1177/000348949310201109.
The purpose of this study is to point out that contrary to traditional belief, there is a small but significant group of nondiabetic patients with malignant external otitis. Thirty patients with a diagnosis of malignant external otitis were treated and followed up at the Department of Otolaryngology-Head and Neck Surgery, Beilinson Medical Center, between 1987 and 1991. Nine of these patients did not have clinical or laboratory evidence of diabetes. This study analyzes this group and concludes that the diagnosis of malignant external otitis should be considered by the treating physician in nondiabetic patients presenting with a Pseudomonas aeruginosa infection of the external ear canal. Severe pain and edematous closure of the canal, together with typical granulation tissue and failure to respond to medical treatment, are specific characteristics of this group.
本研究的目的是指出,与传统观念相反,存在一小部分但数量可观的非糖尿病患者患有恶性外耳道炎。1987年至1991年间,30例被诊断为恶性外耳道炎的患者在贝林森医疗中心耳鼻咽喉头颈外科接受治疗并进行随访。其中9例患者没有糖尿病的临床或实验室证据。本研究对这组患者进行分析并得出结论,对于出现外耳道铜绿假单胞菌感染的非糖尿病患者,治疗医生应考虑恶性外耳道炎的诊断。严重疼痛、耳道水肿闭塞,以及典型的肉芽组织和对药物治疗无反应是该组患者的特定特征。