Bodokh I, Lacour J P, Perrin C, Rosenthal E, Garnier G, Pesce A, Ortonne J P
Service de Dermatologie, Hôpital Pasteur, Nice.
Ann Dermatol Venereol. 1993;120(4):303-4.
We report a case of erythroderma revealing lymphoblastic leukaemia occurring immediately after myelodysplasia. The patient was an 87-year old man admitted for poor general condition, lymph node enlargement and pruriginous oedematous erythroderma. Laboratory examinations showed tricytopenia, bone marrow invasion by lymphoblasts in a myelodysplastic environment of the refractory anaemia type with excess of blasts, and a cutaneous lymphocytic infiltrate with non-blastic lymph node reaction. Owing to its morphological and immunohistological features, the lymphocytic infiltrate was regarded as non-specific. We could not help comparing this case to the other non-specific cutaneous lesions of refractory anaemia which usually reflect transformation into leukaemia.
我们报告一例红皮病，其在骨髓增生异常后立即出现，提示淋巴细胞白血病。患者为一名87岁男性，因全身状况差、淋巴结肿大及瘙痒性水肿性红皮病入院。实验室检查显示三系血细胞减少，在难治性贫血伴原始细胞增多型的骨髓增生异常环境中存在原始淋巴细胞骨髓浸润，以及皮肤淋巴细胞浸润伴非原始细胞性淋巴结反应。由于其形态学和免疫组织学特征，淋巴细胞浸润被认为是非特异性的。我们不禁将此病例与通常反映向白血病转化的难治性贫血的其他非特异性皮肤病变进行比较。
