Mariani R, Taleb-Figueroa A, Bastiani-Griffet F, Monpoux F, Coussement A, Loubière R
Service de Pédiatrie, Hôpital de Cimiez, Nice.
Ann Pediatr (Paris). 1993 Sep;40(7):438-43.
Sertoli-Leydig tumors stem from the mesenchyma and sexual cords of the embryonic gonad. Two cases are reported. One manifested as symptoms of virilization in a 12 year old girl. The other patient developed adnexal torsion at the age of five years. Pelvic ultrasonography visualized the tumor in both cases. Increased production of ovarian androgens suggested the diagnosis in the first case. Histological studies disclosed intermediate differentiation in the first case and tubular differentiation in the second. These tumors usually exhibit low-grade malignancy and unilateral salpingo-oophorectomy ensures recovery in most instances.
支持细胞-间质细胞瘤起源于胚胎性腺的间充质和性索。本文报告了两例病例。一例为一名12岁女孩出现男性化症状。另一例患者在5岁时发生附件扭转。两例病例经盆腔超声检查均发现了肿瘤。第一例病例中卵巢雄激素分泌增加提示了诊断。组织学研究显示，第一例为中间分化，第二例为管状分化。这些肿瘤通常表现为低度恶性，大多数情况下，单侧输卵管卵巢切除术可确保康复。
