Taniguchi M H, Hayes J, Rodriguez A A
Department of Rehabilitation Medicine, Columbus Childrens Hospital, OH 43205.
Arch Phys Med Rehabil. 1993 Nov;74(11):1139-43.
Two hundred consecutive ulnar F wave latencies were evaluated in 30 healthy controls (C) and in 9 patients with mild neuropathy (N). The primary study objective was to determine the F wave sample size required to obtain a reliable F mean latency. A secondary objective was to explore the diagnostic utility of three F wave parameters: the minimal F wave latency (Fmin), the average F wave latency (Fmean), and the minimal-maximal F wave latency difference (Frange). For the control group, the Fmean reliability estimates as measured by intraclass correlation coefficients were 0.87, 0.97, and 0.99 with 1, 5, and 10 responses, respectively; for the N group, the corresponding values were 0.73, 0.93, and 0.96. Fmean was abnormal in 89% of the subjects with mild neuropathy whereas Frange and Fmin were abnormal in 67% and 33%, respectively. The study suggests (1) a reliable F mean latency can be obtained by averaging ten F responses; and (2) Fmean and Frange offers promise in increasing the diagnostic utility of the F response in identifying mild neuropathies.
对30名健康对照者（C组）和9名轻度神经病变患者（N组）的200个连续尺神经F波潜伏期进行了评估。主要研究目的是确定获得可靠的F波平均潜伏期所需的F波样本量。次要目的是探讨三个F波参数的诊断效用：最小F波潜伏期（Fmin）、平均F波潜伏期（Fmean）和最小-最大F波潜伏期差值（Frange）。对于对照组，通过组内相关系数测量的Fmean可靠性估计值在分别有1次、5次和10次反应时为0.87、0.97和0.99；对于N组，相应的值为0.73、0.93和0.96。在轻度神经病变患者中，89%的受试者Fmean异常，而Frange和Fmin异常的比例分别为67%和33%。该研究表明：（1）通过平均10次F反应可获得可靠的F波平均潜伏期；（2）Fmean和Frange有望提高F反应在识别轻度神经病变中的诊断效用。
