Saade G R, Moise K J, Belfort M A, Hesketh D E, Carpenter R J
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Tex. 77030.
Fetal Diagn Ther. 1993 May-Jun;8(3):161-4. doi: 10.1159/000263816.
The purpose of this study was to determine whether the need for late neonatal transfusion can be predicted in fetuses who received intrauterine transfusions. The records of 36 patients who underwent intrauterine transfusion were reviewed. Newborns who required late transfusions had a lower reticulocyte count at their last intrauterine transfusion, a longer duration between their lowest fetal reticulocyte count and delivery, and a higher umbilical cord blood hemoglobin and percent adult red cells on Kleihauer-Betke stain at delivery. The need for late transfusions appears to be related to the extent and duration of fetal bone marrow suppression.
本研究的目的是确定对于接受宫内输血的胎儿，是否能够预测其晚期新生儿输血的需求。回顾了36例行宫内输血患者的记录。需要晚期输血的新生儿在末次宫内输血时网织红细胞计数较低，最低胎儿网织红细胞计数与分娩之间的时间间隔较长，且分娩时脐血血红蛋白及Kleihauer-Betke染色的成人红细胞百分比更高。晚期输血的需求似乎与胎儿骨髓抑制的程度和持续时间有关。
