Blessed W B, Coughlin J P, Johnson M P, Evans M I, Jewell M R, Goyert G L, Schwartz D B, Klein M D
Department of Obstetrics and Gynecology, Hutzel and Sinai Hospital, Detroit, Mich.
Fetal Diagn Ther. 1993 May-Jun;8(3):203-8. doi: 10.1159/000263826.
Eighteen patients with a prenatal diagnosis of fetal abdominal wall defect were delivered by cesarean section and repaired either immediately (begun within 15 min, n = 9), or by the traditional (delayed) method (n = 9, average delay = 4.4 h). Neonates repaired immediately had comparable gestational ages and birthweight, however, subjectively had less edematous bowel with less fibrous peel. These fetuses were more likely to be closed primarily (7/9 vs. 4/9), spent less time on a ventilator (8.1 vs. 17.9 days), seemed to be fed sooner (7.6 vs. 17.9 days), and discharged home earlier (14.3 vs. 24.0 days). Our results suggest that for fetuses delivered by cesarean section, early defect repair may reduce bowel edema and fibrous peel formation thus facilitating primary closure, with earlier ventilator weaning, feeding and discharge home.
18例产前诊断为胎儿腹壁缺损的患者通过剖宫产分娩,并立即(在15分钟内开始,n = 9)或采用传统(延迟)方法进行修复(n = 9,平均延迟 = 4.4小时)。立即修复的新生儿胎龄和出生体重相当,但主观上肠水肿较轻,纤维膜较少。这些胎儿更有可能一期闭合(7/9 vs. 4/9),使用呼吸机的时间更短(8.1天 vs. 17.9天),似乎更早开始喂养(7.6天 vs. 17.9天),更早出院回家(14.3天 vs. 24.0天)。我们的结果表明,对于剖宫产分娩的胎儿,早期修复缺损可能减少肠水肿和纤维膜形成,从而促进一期闭合,更早撤机、开始喂养并出院回家。