Stefos T, Georgiou I, Syrrou M, Lollis D
Department of Obstetrics and Gynecology, University of Ioannina, Greece.
Fetal Diagn Ther. 1993 May-Jun;8(3):211-3. doi: 10.1159/000263828.
Fetal intestinal tract abnormalities can be pregnancy complications at all maternal ages. There have been reports of ultrasound identification of these abnormalities, particularly of fetal intestinal obstructions. We report the first case to our knowledge of elevated levels of the intestinal isozyme, alkaline phosphatase, in the amniotic fluid and blood serum and also the presence of prealbumin in the amniotic fluid of a fetus with extensive intestinal distension and polyhydramnios. It was revealed that the alkaline phosphatase intestinal isozyme as well as protein electrophoresis for abnormal albumin bands in the amniotic fluid are valuable markers for the early diagnosis of the above-mentioned fetal abnormalities.
胎儿肠道异常在所有年龄段的孕妇中都可能成为妊娠并发症。已有关于超声识别这些异常情况的报道，尤其是胎儿肠梗阻。据我们所知，我们报告了首例羊水和血清中肠道同工酶碱性磷酸酶水平升高，且羊水存在前白蛋白的病例，该胎儿有广泛的肠道扩张和羊水过多。结果表明，羊水碱性磷酸酶肠道同工酶以及羊水异常白蛋白条带的蛋白质电泳是上述胎儿异常早期诊断的有价值标志物。
