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Novel approaches to the control of graft versus host disease.

作者信息

Sykes M

机构信息

Harvard Medical School, Boston.

出版信息

Curr Opin Immunol. 1993 Oct;5(5):774-81. doi: 10.1016/0952-7915(93)90136-g.

DOI:10.1016/0952-7915(93)90136-g
PMID:8240740
Abstract

Graft versus host disease (GVHD) remains the major obstacle to the application of bone marrow transplantation across HLA barriers. Recent advances in our understanding of GVHD pathophysiology have resulted in the evaluation in animal models and in clinical trials of some novel approaches to avoiding and treating GVHD. Continued advances in our knowledge are likely to result in the clinical application of biological therapies to maximize graft versus leukemia effects and alloengraftment, while avoiding GVHD.

摘要

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引用本文的文献

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Prevention of Transplant Rejection: Can Tolerance be Achieved with Immunosuppressive Treatment?移植排斥反应的预防:免疫抑制治疗能否实现免疫耐受?
Clin Immunother. 1996 Aug;6(2):89-96. doi: 10.1007/BF03259505.
2
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Ann Hematol. 1995 Nov;71(5):209-17. doi: 10.1007/BF01744370.