Chao C R, Glenford P G, Karibo E J, Salha S D
Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY 10032.
Exp Physiol. 1993 Sep;78(5):707-10. doi: 10.1113/expphysiol.1993.sp003718.
We sought to determine the cerebral metabolic fate of glucose during sound stimulation in near-term fetal sheep. Blood oxygen content was significantly decreased by 6-7% during sound stimulation. The cerebral glucose:oxygen quotient increased from 0.88 +/- 0.08 to 1.13 +/- 0.12 (mean +/- S.E.M., P < 0.01). This is consistent with the phenomenon of stimulated glycolysis which has been shown to increase brain lactate concentration in other models.
我们试图确定近足月胎羊在声音刺激期间葡萄糖的脑代谢去向。声音刺激期间血氧含量显著降低了6 - 7%。脑葡萄糖:氧商从0.88±0.08增加到1.13±0.12（均值±标准误，P<0.01）。这与刺激糖酵解现象一致，在其他模型中已表明刺激糖酵解会增加脑乳酸浓度。
