人脑中酯酶的对映体选择性。
Enantioselectivity of esterases in human brain.
作者信息
Yang S K, Huang A, Huang J D
机构信息
Department of Pharmacology, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
出版信息
Chirality. 1993;5(7):565-8. doi: 10.1002/chir.530050714.
PMID:8240930
Abstract
Subcellular fractions of three human brain specimens were found to contain esterase activities which hydrolyzed racemic oxazepam 3-acetate (rac-OXA). All three human brain preparations were highly selective toward the S-enantiomer of rac-OXA.
摘要
在三个人类大脑标本的亚细胞组分中发现了酯酶活性，这些酯酶能够水解外消旋奥沙西泮3-乙酸酯（rac-OXA）。所有三种人类大脑制剂对rac-OXA的S-对映体都具有高度选择性。
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