高渗盐溶液（20%）对失血性休克期间心脏动力学的影响。
Effects of hypertonic saline solution (20%) on cardiodynamics during hemorrhagic shock.
作者信息
Ogata H, Luo X X
机构信息
First Department of Anesthesiology, School of Medicine, Dokkyo University, Tochigi Prefecture, Japan.
出版信息
Circ Shock. 1993 Oct;41(2):113-8.
The cardiodynamic effects of using hypertonic saline solution were analyzed in dogs after inducing hemorrhagic shock. Administration of 1.5 mL/kg 20% sodium chloride resulted in circulatory improvement: 200% increase in blood pressure, 260% increase in cardiac output, 60-70% increase in pulmonary arterial pressure, 66% increase in pulmonary wedge pressure, 200% increase in central venous pressure, 33% decrease in total peripheral resistance, and 40% decrease in pulmonary vascular resistance. The effects of sodium chloride on cardiodynamics probably resulted in elevation of preload and reduction of afterload.
在诱导犬失血性休克后，分析了使用高渗盐溶液的心脏动力学效应。给予1.5 mL/kg 20%氯化钠可改善循环：血压升高200%，心输出量增加260%，肺动脉压升高60 - 70%，肺楔压升高66%，中心静脉压升高200%，总外周阻力降低33%，肺血管阻力降低40%。氯化钠对心脏动力学的影响可能导致前负荷升高和后负荷降低。
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