Zhu X W
Second Municipal Hospital, Wuhan.
Zhonghua Fu Chan Ke Za Zhi. 1993 May;28(5):275-7, 313.
Among 61 patients with severe pregnancy induced hypertension, cerebral lesions were detected on CT scans in 23 cases (37.7%). The positive rates were 5/25 cases in preeclampsia and 18/36 cases in eclampsia. The incidence rate of cerebral lesions in eclampsia was significantly higher than that in preeclampsia (chi 2 test, P < 0.05). Furthermore, it showed that patients with renal impairment and retinal changes were more susceptible to cerebral lesions (P < 0.05), through comparative study of the relationships between either the function of liver and kidney or retinal changes and cerebral lesions. Main manifestations of cerebral lesions were ischemia, edema and infarction. The represented the different pathological stage of cerebral lesions. The cerebral lesions were mainly involved at cortical or subcortical area of bilateral parietal or occipital lobe (60%), secondly at the deep basal ganglia and the superior sagittal sinus. The pathological process of cerebral lesions and the management of pregnancy induced hypertension were analysed.
在61例重度妊娠高血压综合征患者中,CT扫描发现23例(37.7%)有脑部病变。子痫前期25例中有5例阳性,子痫36例中有18例阳性。子痫患者脑部病变的发生率明显高于子痫前期患者(卡方检验,P<0.05)。此外,通过对肝肾功或视网膜改变与脑部病变之间关系的对比研究发现,有肾功能损害和视网膜改变的患者更容易发生脑部病变(P<0.05)。脑部病变的主要表现为缺血、水肿和梗死。它们代表了脑部病变的不同病理阶段。脑部病变主要累及双侧顶叶或枕叶的皮质或皮质下区域(60%),其次是深部基底节和上矢状窦。分析了脑部病变的病理过程及妊娠高血压综合征的处理。