Wiu J J
Anti-epidemic and Sanitation Station of Zhengzhou, He'nan Province.
Zhonghua Yu Fang Yi Xue Za Zhi. 1993 May;27(3):160-1.
The authors studied the epidemic features of epidemic cerebrospinal meningitis before and after mass vaccination with Purified meningococcal polysaccharide vaccine group A. After the mass vaccination, the morbidity rate of epidemic cerebrospinal meningitis fell considerably year after year. The epidemic cycle changed for the first time. The ratio of the number of cases in the city to those in the countryside was reduced. The phenomenon that the infectious disease spread along traffic lines from city to countryside disappeared. The cases mainly occurred in the remote mountain village. The morbidity rate in the group of 0-3 years relatively increased. The level of antibody titers in population obviously increased. The carrier rate of meningococci and constituent ratio of group A reduced. The epidemic group was group A, but cases of group C occurred for the first time.
作者研究了A群脑膜炎球菌多糖菌苗大规模接种前后流行性脑脊髓膜炎的流行特征。大规模接种后，流行性脑脊髓膜炎发病率逐年大幅下降。流行周期首次发生改变。城市与农村病例数之比降低。传染病沿交通线路由城市向农村传播的现象消失。病例主要发生在偏远山村。0至3岁组发病率相对上升。人群抗体滴度水平明显提高。脑膜炎球菌带菌率及A群构成比降低。流行菌群为A群，但首次出现C群病例。
