[通过计算机图像分析对糖尿病视网膜病变进行定量研究]

[Quantitative study of diabetic retinopathy by computerized image analysis].

作者信息

Zhang H R, Tian L

机构信息

Department of Ophthalmology, Third Teaching Hospital, Beijing Medical University.

出版信息

Zhonghua Yan Ke Za Zhi. 1993 Jul;29(4):218-20.

PMID:8243193

Abstract

Composite fluorescein angiographic pictures of 66 eyes with diabetic retinopathy and nonperfusion areas were studied by computerized image analysis, and the ratio of the nonperfusion area to the disc area was calculated. There were 49 eyes with neovascularization (NV), in which the mean ratio +/- standard error was 46.33 +/- 7.01 (8.15 to 298.26), and the corresponding value in the other 17 eyes without NV was 6.90 +/- 1.31 (2.20 to 21.37), the difference being very significant. When the ratios were under 10, from 10 to 30, or over 30, the percentages of eyes manifesting NV were 13.3%, 81.8% and 100% respectively. In the 49 eyes with NV, the majority of the total 267 neovascular clusters were distributed 4-6 DD away from the optic disc, which itself was involved only in 18 eyes.

摘要

通过计算机图像分析研究了66只患有糖尿病性视网膜病变和无灌注区的眼睛的复合荧光血管造影图片，并计算了无灌注区与视盘面积的比值。有49只眼睛出现新生血管（NV），其平均比值±标准误差为46.33±7.01（8.15至298.26），另外17只无NV的眼睛的相应值为6.90±1.31（2.20至21.37），差异非常显著。当比值低于10、在10至30之间或高于30时，出现NV的眼睛百分比分别为13.3%、81.8%和100%。在49只出现NV的眼睛中，267个新生血管簇中的大多数分布在距视盘4 - 6视盘直径（DD）处，视盘本身仅累及18只眼睛。