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Subzonal sperm insemination and total or extreme asthenozoospermia: an effective technique for an uncommon cause of male infertility.

作者信息

Terriou P, Giorgetti C, Hans E, Spach J L, Salzmann J, Carlon N, Navarro A, Roulier R

机构信息

Institut de Médecine de la Reproduction, Faculté de la Timone, Marseille, France.

出版信息

Fertil Steril. 1993 Dec;60(6):1057-61. doi: 10.1016/s0015-0282(16)56410-3.

DOI:10.1016/s0015-0282(16)56410-3
PMID:8243686
Abstract

OBJECTIVE

To assess the value of subzonal insemination (SUZI) in cases of total or extreme asthenozoospermia.

DESIGN

The results of IVF after SUZI were assessed in six cycles (four couples) with documented asthenozoospermia.

SETTING

Institut de Médecine de la Reproduction, Marseille, France.

PATIENTS

Four couples underwent six retrieval cycles. In all cases asthenozoospermia was total (100% of immotile spermatozoa) or extreme (5% nonprogressive motility). Oligozoospermia and teratozoospermia were ruled out in all cases. In two cases electron microscopy revealed the absence of the central singlet in the flagellum axonemal complex and in one case a major dysplasia of the fibrous sheath in the flagellum principal piece.

RESULTS

The overall fertilization rate was 45%. The diploid embryo rate was 33%. Embryo quality was satisfactory. In five of six cycles, three embryos were transferred. Two triplet pregnancies were obtained corresponding to an implantation rate per transferred embryo of 40%.

CONCLUSION

Total or extreme asthenozoospermia seems to be a good indication for SUZI.

摘要

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Subzonal sperm insemination and total or extreme asthenozoospermia: an effective technique for an uncommon cause of male infertility.
Fertil Steril. 1993 Dec;60(6):1057-61. doi: 10.1016/s0015-0282(16)56410-3.
2
Comparison of SUZI and ICSI for severe male factor.严重男性因素患者中苏兹法(SUZI)与卵胞浆内单精子注射(ICSI)的比较。
Hum Reprod. 1995 Nov;10(11):2941-4. doi: 10.1093/oxfordjournals.humrep.a135824.
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Evaluation of a cut-off value for normal sperm morphology using strict criteria to predict fertilization after conventional in-vitro fertilization and embryo transfer in asthenozoospermia.使用严格标准评估正常精子形态的临界值,以预测弱精子症患者常规体外受精和胚胎移植后的受精情况。
Hum Reprod. 1996 Oct;11(10):2155-61. doi: 10.1093/oxfordjournals.humrep.a019068.
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Sperm characteristics and outcome of human assisted fertilization by subzonal insemination and intracytoplasmic sperm injection.精子特征与人类通过透明带下授精和卵胞浆内单精子注射辅助受精的结果。
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Pregnancy after subzonal insemination with spermatozoa lacking outer dynein arms.使用缺乏外动力蛋白臂的精子进行透明带下授精后的妊娠。
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Fertilizing ability of immotile spermatozoa after intracytoplasmic sperm injection.卵胞浆内单精子注射后不动精子的受精能力
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A comparative analysis of embryo implantation potential in patients with severe teratozoospermia undergoing in-vitro fertilization with a high insemination concentration or intracytoplasmic sperm injection.对严重畸形精子症患者采用高授精浓度体外受精或卵胞浆内单精子注射时胚胎着床潜力的比较分析。
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Subzonal insemination: a prospective randomized study in patients with abnormal sperm morphology.卵周隙内授精:一项针对精子形态异常患者的前瞻性随机研究。
Fertil Steril. 1993 Aug;60(2):307-13. doi: 10.1016/s0015-0282(16)56103-2.
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Subzonal insemination, partial zona dissection or intracytoplasmic sperm injection? An easy decision?卵周隙内授精、部分透明带切开术还是卵胞浆内单精子注射?这是个容易做出的决定吗?
Hum Reprod. 1995 Jan;10(1):165-70. doi: 10.1093/humrep/10.1.165.

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