Wiese K G, Merten H A
Department of Maxillofacial Surgery, Georg-August-University, Göttingen, Germany.
Int J Oral Maxillofac Surg. 1993 Oct;22(5):306-8. doi: 10.1016/s0901-5027(05)80522-3.
The role of the periosteum in the osteointegration of hydroxyapatite (HA) granules was studied in the skull and tibial bone of eight adult Göttingen minipigs. Calcein and tetracycline were used as labeling stains to determine new bone formation. Depending on the condition of the periosteum, three different patterns of osteointegration of HA were found.
在八只成年哥廷根小型猪的颅骨和胫骨中研究了骨膜在羟基磷灰石（HA）颗粒骨整合中的作用。使用钙黄绿素和四环素作为标记染料来确定新骨形成。根据骨膜的状况，发现了HA骨整合的三种不同模式。
