King L R, Siegel M J, Solomon A L
Mallinckrodt Institute of Radiology, St. Louis, MO 63110.
J Ultrasound Med. 1993 Oct;12(10):577-81. doi: 10.7863/jum.1993.12.10.577.
The real-time pelvic sonograms of 32 girls under 8 years old with true isosexual precocity (23 cases), pseudosexual precocity (four cases), premature adrenarche (four cases), and an undetermined problem (one case) were evaluated retrospectively for ovarian volume and presence and size of cysts. Sonographic findings were compared to those of 181 age-matched controls to determine the best sonographic indicator of precocious puberty. Ovarian volume was 4.6 cm3 in girls with true isosexual precocity, 4.1 cm3 in girls with pseudosexual precocity, and less than 1 cm3 in the other patients as well as in the control population. Ovarian enlargement was bilateral in true precocity and unilateral in pseudosexual precocity. Of the 181 subjects in the control group, 96 (53%) had ovarian cysts, almost all of which were small (less than 9 mm in diameter). Ovarian cysts occurred in 22 of 32 patients (69%) with precocity. The cysts generally were smaller than 9 mm in true isosexual precocity and larger than 9 mm in pseudosexual precocity. In conclusion, small ovarian cysts are not specific to precocious puberty and its various subtypes. Bilateral ovarian enlargement appears to be a reliable indicator of true isosexual puberty, whereas unilateral ovarian enlargement in combination with macrocysts is suggestive of pseudosexual precocity.
对32名8岁以下真性同性性早熟女童（23例）、假性性早熟女童（4例）、肾上腺功能初现提前女童（4例）及病因未明女童（1例）的实时盆腔超声检查结果进行回顾性评估，分析卵巢体积以及囊肿的有无和大小。将超声检查结果与181名年龄匹配的对照者进行比较，以确定性早熟的最佳超声指标。真性同性性早熟女童的卵巢体积为4.6立方厘米，假性性早熟女童为4.1立方厘米，其他患者及对照人群的卵巢体积均小于1立方厘米。真性性早熟时卵巢增大为双侧性，假性性早熟时为单侧性。对照组的181名受试者中，96名（53%）有卵巢囊肿，几乎所有囊肿都较小（直径小于9毫米）。32例性早熟患者中有22例（69%）出现卵巢囊肿。真性同性性早熟时囊肿一般小于9毫米，假性性早熟时囊肿大于9毫米。总之，小卵巢囊肿并非性早熟及其各亚型所特有。双侧卵巢增大似乎是真性同性性早熟的可靠指标，而单侧卵巢增大伴大囊肿提示假性性早熟。
