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[胰腺坏死。当前观点与展望]

[Pancreonecrosis. Current views and perspectives].

作者信息

Savelév V S, Kubyshkin V A

出版信息

Khirurgiia (Mosk). 1993 Jun(6):22-8.

PMID:8246382
Abstract

Generalization of data gained from the case records of patients with pancreonecrosis treated at 14 hospitals of Moscow allowed the authors to mark out typical errors in the diagnosis and therapeutic tactics which caused, to a considerable measure, mortality in 58.1 cases. From their personal experience in the treatment of such patients the authors believe it possible to improve essentially the diagnosis of acute pancreatitis by wide use of laparoscopy, ultrasonic scanning, and angiography of the pancreas for early verification of pancreonecrosis, appraisal of the condition of the extrahepatic bile ducts, and application of mildly injurious methods of treatment. Setting apart only two forms of acute pancreatitis is substantiated from the clinico-anatomical standpoint. The choice of the therapeutic tactics in pancreonecrosis should be based on the severity of the disease and the dynamics of its development during intensive therapy, rather than on the morphological diagnosis. Using the criteria of evaluation of the severity of pancreonecrosis, the authors reduced considerably the frequency of operative interventions in the early stages of the disease. Among the methods of operative treatment of pancreonecrosis, distant pancreatectomy or programmed repeated necroso-sequestrectomies are preferred.

摘要

对莫斯科14家医院治疗的胰腺坏死患者病例记录所获数据进行归纳总结后,作者们明确了诊断和治疗策略中的典型错误,这些错误在很大程度上导致了58.1例患者死亡。基于他们治疗此类患者的个人经验,作者们认为通过广泛应用腹腔镜检查、超声扫描和胰腺血管造影以早期确诊胰腺坏死、评估肝外胆管状况并采用轻度损伤性治疗方法,可从根本上改善急性胰腺炎的诊断。从临床解剖学角度来看,仅区分两种急性胰腺炎形式是有依据的。胰腺坏死治疗策略的选择应基于疾病的严重程度及其在强化治疗期间的发展动态,而非形态学诊断。运用评估胰腺坏死严重程度的标准,作者们大幅降低了疾病早期手术干预的频率。在胰腺坏死的手术治疗方法中,更倾向于行远端胰腺切除术或计划性重复坏死组织清除术。

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