Romaszko J P, Tridon A, Jouanel P, Subtil E, Dibet P, Betail G
Laboratoire d'Immunologie, Faculté de Pharmacie, Clermont-Ferrand, France.
Pathol Biol (Paris). 1993 Jun;41(6):525-9.
During an 11-month period, 270 cryoglobulins were identified in 735 sera from patients versus 34 in 82 sera from apparently healthy blood donors. Western-blot analysis of the cryoglobulins was performed and cryoglobulin protein content was determined using a colorimetric assay. Comparison of findings in the two groups suggested that a substantial proportion of cryoglobulins identified in the sera of patients are quantitatively and qualitatively indistinguishable from cryoglobulins identified in healthy controls.
在11个月的时间里，从患者的735份血清中鉴定出270种冷球蛋白，而在看似健康的献血者的82份血清中仅鉴定出34种。对冷球蛋白进行了蛋白质印迹分析，并使用比色测定法测定了冷球蛋白的蛋白质含量。两组结果的比较表明，在患者血清中鉴定出的相当一部分冷球蛋白在数量和质量上与在健康对照中鉴定出的冷球蛋白没有区别。
