Sander C M
Department of Pathology, Michigan State University, East Lansing 48824.
Pediatr Pathol. 1993 Sep-Oct;13(5):621-33. doi: 10.3109/15513819309048250.
Five placentas referred to the Michigan Placental Tissue Registry between 1982 and 1992 exhibited an unusual malformation of chorionic stem vessels. Multiple intestine-like tangles arising from umbilical vessels rested on and entered the chorionic plate. This anomaly appears similar to the "unusual vascular anomaly of the placenta" reported by Lee et al. (Am J Clin Pathol 1991; 95:48-51). In addition, amnionic-type bands were often adherent to the vascular complex. In three cases, clusters of macrocystic villi interspersed by normal placental parenchyma resulted in a partial molar appearance. Two of the infants were stillborn; three were liveborn. Congenital anomalies were not recognized in other organs. Flow cytometric analysis of placental tissue from four specimens disclosed a diploid chromosomal pattern. This rare anomaly complex appears to be a malformation involving the extraembryonic mesoderm rather than a cytogenetic error.
1982年至1992年间提交至密歇根胎盘组织登记处的五份胎盘呈现出绒毛膜干血管的异常畸形。多条类似肠道的缠结物从脐血管长出，附着于并进入绒毛膜板。这种异常情况似乎与Lee等人报道的“胎盘异常血管畸形”相似（《美国临床病理学杂志》1991年；95:48 - 51）。此外，羊膜样带常附着于血管复合体。在三例中，散在正常胎盘实质的大囊状绒毛簇导致部分葡萄胎外观。其中两名婴儿为死产；三名婴儿为活产。其他器官未发现先天性异常。对四个标本的胎盘组织进行流式细胞术分析显示为二倍体染色体模式。这种罕见的异常复合体似乎是一种涉及胚外中胚层的畸形，而非细胞遗传学错误。
