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[蜱传脑炎复合体病毒经口感染猴免疫发生过程中几种酶活性的组织化学研究]

[Histochemical study of the activity of several enzymes in the process of immunogenesis in monkeys orally infected with viruses of the tick-borne encephalitis complex].

作者信息

Dubov A V, Gladyshev S P

出版信息

Vopr Virusol. 1976 May-Jun(3):337-41.

PMID:824823
Abstract

The activity of succinate dehydrogenase, acid and alkaline phosphatase was studied histochemically in immunocompetent organs of Macacus rhesus monkeys orally infected with viruses of the tick-borne encephalitis complex with different biological properties. A gradual increase in the activity of acid phosphatase and succinate dehydrogenase was observed by the 10th--15th day of the experiment followed by its decline to normal by 90 days. The content of alkaline phosphatase in lympoid organs diminished markedly in the first day of the study and then increased by 15--30 days after antigenic stimulation.

摘要

对口服感染具有不同生物学特性的蜱传脑炎复合群病毒的恒河猴免疫活性器官中的琥珀酸脱氢酶、酸性和碱性磷酸酶活性进行了组织化学研究。在实验的第10至15天观察到酸性磷酸酶和琥珀酸脱氢酶活性逐渐增加,随后在90天时降至正常水平。在研究的第一天,淋巴器官中碱性磷酸酶的含量显著减少,然后在抗原刺激后15至30天增加。

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