Biasi G, Gonano N, Santarelli R, Fregonese V, Andolfato G, Pfeiffer P, Nozzon L
Service de chirurgie vasculaire, Hôpital Santa-Maria-de-la-Misericordia, Udine, Italie.
Phlebologie. 1993 Jul-Sep;46(3):501-5.
Large veins LMS is a rare slow growing malignant tumor originating from smooth muscle cells of the media. The authors report a case of LMS of the left common iliac vein propagating to the Inferior Vena Cava that presented with a left femoral-iliac deep thrombophlebitis. CT scan showed an uneven solid mass approximately 5 cm large within the left side of the pelvis. The mass displaced the left iliac artery and compressed the left iliac vein without a significant cleavage surface between the mass itself and the vascular structures. Location was next to the spine, medially and anteriorily to the psoas muscle. A thrombosis could be noticed within the distal segment of the inferior Vena Cava and within the proximal segment of the left iliac vein. US scan with fine needle biopsy of the mass didn't yield significant information. At surgical exploration a neoplastic mass involving and blocking the left iliac vein was found. Veinotomy performed on the iliac vein and on the distal segment of the Inferior Vena Cava but without infiltration of the vein walls. Surgical treatment consisted of asportation of the neoplastic mass, resection of the left iliac vein and thrombectomy of the Inferior Vena Cava. Histologic examination of the operated specimen revealed a mixoid LMS with vascular origin without involvement of the surrounding lymph nodes. Absence of clinical and radiological signs of relapse eight months after surgery makes further surgical and complementary (drug- and radiotherapy) treatments currently unnecessary.
大静脉平滑肌肉瘤是一种罕见的、生长缓慢的恶性肿瘤,起源于中膜的平滑肌细胞。作者报告一例左髂总静脉平滑肌肉瘤蔓延至下腔静脉,表现为左股-髂深静脉血栓形成。CT扫描显示盆腔左侧有一个大小约5cm的不均匀实性肿块。肿块使左髂动脉移位并压迫左髂静脉,肿块与血管结构之间无明显分界平面。位置靠近脊柱,位于腰大肌内侧和前方。在下腔静脉远端和左髂静脉近端可见血栓形成。对肿块进行细针穿刺活检的超声扫描未获得重要信息。手术探查发现一个肿瘤性肿块累及并阻塞左髂静脉。对髂静脉和下腔静脉远端进行静脉切开,但未侵犯静脉壁。手术治疗包括切除肿瘤性肿块、切除左髂静脉和下腔静脉血栓切除术。手术标本的组织学检查显示为血管源性黏液样平滑肌肉瘤,未累及周围淋巴结。术后8个月无临床和影像学复发迹象,目前无需进一步手术及辅助(药物和放疗)治疗。