Garufi A, Priolo G D, Coppolino F, Giammusso B, Materazzo S
Cattedra di Radiologia Generale e Speciale Odontostomatologica, Università di Catania.
Radiol Med. 1993 Oct;86(4):489-95.
Computed Tomography (CT) is an indispensable noninvasive method for staging transitional cell carcinomas of renal pelvis and ureter. Twenty-seven patients with upper urinary tract tumors were examined and the CT results correlated with histopathologic findings. These tumors exhibit three different development patterns: in our series we identified 17 intraluminal sessile lesions, 6 focal or concentric wall thickenings and finally 7 infiltrating masses; soft-tissue density lesions exhibited in all cases mild contrast enhancement (mean density increase: 38 HU). Even though the attenuation values of tumors do not allow the accurate demonstration of the depth of renal pelvis and ureteral wall invasion, CT can differentiate the lesions which are still confined within the external wall layers (CT1, 17 cases) from those invading the peripelvic-ureteral fat (CT2, 9 cases) or spreading to other organs as well as distant metastases (CT3, 4 cases). Delayed scans can also demonstrate intraluminal lesion extent and sometimes changes of patients' position allow better differentiation of wall outlines from peripheral fat. The overall staging accuracy of CT was 76.66% and its sensitivity was 93.33%. The assessment of lymph node metastases was the major cause of error in the CT evaluation of these tumors.
计算机断层扫描(CT)是肾盂和输尿管移行细胞癌分期不可或缺的无创方法。对27例上尿路肿瘤患者进行了检查,并将CT结果与组织病理学结果进行了对比。这些肿瘤呈现出三种不同的发展模式:在我们的系列研究中,我们识别出17例腔内无蒂病变、6例局灶性或同心性壁增厚,以及最后7例浸润性肿块;所有病例中的软组织密度病变均表现出轻度强化(平均密度增加:38 HU)。尽管肿瘤的衰减值无法准确显示肾盂和输尿管壁的浸润深度,但CT能够区分仍局限于外壁层内的病变(CT1,17例)与侵犯肾盂周围-输尿管脂肪的病变(CT2,9例)或扩散至其他器官以及远处转移的病变(CT3,4例)。延迟扫描还可显示腔内病变范围,有时患者体位的改变有助于更好地区分壁轮廓与周围脂肪。CT的总体分期准确率为76.66%,其敏感性为93.33%。在这些肿瘤的CT评估中,对淋巴结转移的评估是主要的误差来源。